Phenotypes for Dlx5 Trp63 MGI:3797869 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Dlx5^tm1Levi/Dlx5/Dlx6^tm1Levi Trp63^tm1Aam/Trp63^tm1Aam
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlx5/Dlx6^tm1Levi mutation (0 available); any Dlx5 mutation (23 available)
Dlx5^tm1Levi mutation (1 available); any Dlx5 mutation (23 available)
Trp63^tm1Aam mutation (0 available); any Trp63 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal phalanx morphology ( J:135784 )

• mice exhibit dysmorphologies of the most proximal segments of the central phalanges

• in 2 of 3 mice the posterior fingers are missing

ectrodactyly ( J:135784 )

• all mice exhibit severe ectrodactyly in the hindlimbs with two to four fingers missing

monodactyly ( J:135784 )

• in one mouse

syndactyly ( J:135784 )

• in hind- and forelimbs

skeleton

abnormal phalanx morphology ( J:135784 )

• mice exhibit dysmorphologies of the most proximal segments of the central phalanges

• in 2 of 3 mice the posterior fingers are missing

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23