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Phenotypes Associated with This Genotype
Genotype
MGI:3797235
Allelic
Composition		 Syktm1Kuro/Syktm1Kuro
Zap70tm1Dlo/Zap70tm1Dlo
Cd79atm1(cre)Reth/?
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (29 available)
Syktm1Kuro mutation (0 available); any Syk mutation (45 available)
Zap70tm1Dlo mutation (0 available); any Zap70 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal pro-B cell differentiation ( J:134528 )
• there is a complete block pro-B cell differentation at the BP-1+HASlow stage

hematopoietic system
abnormal pro-B cell differentiation ( J:134528 )
• there is a complete block pro-B cell differentation at the BP-1+HASlow stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory