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Phenotypes Associated with This Genotype
Genotype
MGI:3796553
Allelic
Composition		 Gna11tm1Soff/Gna11tm1Soff
Gnaqtm2Soff/Gnaq+
Tg(PTH-cre)4167Slib/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gna11tm1Soff mutation (0 available); any Gna11 mutation (25 available)
Gnaqtm2Soff mutation (0 available); any Gnaq mutation (24 available)
Tg(PTH-cre)4167Slib mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:116986 )
• reduced at P9 compared to controls

homeostasis/metabolism
increased circulating parathyroid hormone level ( J:116986 )
• levels are increased compared to controls
abnormal circulating calcium level ( J:116986 )
• increased relative to controls at P9
abnormal urine calcium level ( J:116986 )
• increased relative to controls

renal/urinary system
abnormal urine calcium level ( J:116986 )
• increased relative to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory