Analysis Tools
hematopoietic system
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• pro-B cell apoptosis is observed in mice after induced cre expression
• viability of immature and mature B cells in the bone marrow is not affected by conditional ablation of Mirn17-92
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• pro-B cells have normal D(H) to J(H) recombination, but V(H) to DJ(H) recombination is less efficient than in wild-type
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• 2-month old mice injected with pI:pC to induce cre expression were found to have reduced numbers of pre-B cells in the bone marrow at 4 weeks after injection
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immune system
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• pro-B cell apoptosis is observed in mice after induced cre expression
• viability of immature and mature B cells in the bone marrow is not affected by conditional ablation of Mirn17-92
|
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• pro-B cells have normal D(H) to J(H) recombination, but V(H) to DJ(H) recombination is less efficient than in wild-type
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• 2-month old mice injected with pI:pC to induce cre expression were found to have reduced numbers of pre-B cells in the bone marrow at 4 weeks after injection
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cellular
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• pro-B cell apoptosis is observed in mice after induced cre expression
• viability of immature and mature B cells in the bone marrow is not affected by conditional ablation of Mirn17-92
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