Phenotypes Associated with This Genotype

Genotype
MGI:3794990

• Allelic Composition: Rela^tm1.1Gho/Rela^tm1.1Gho; Tnfrsf1a^tm1Mak/Tnfrsf1a^tm1Mak
• Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:134684 )

• a few mice survived to birth died about 1 month after birth

prenatal lethality, incomplete penetrance ( J:134684 )

• most homozygous mice died in utero before birth

• very small number of mutant mice survived to birth

vision/eye

abnormal eye development ( J:134684 )

• a few mice survived to birth show eye developmental defect and were blind

blindness ( J:134684 )

• a few mice survived to birth show eye developmental defect and were blind