Phenotypes Associated with This Genotype

Genotype
MGI:3790813

• Allelic Composition: Bmi1^tm1Brn/Bmi1^tm1Brn; E2f6^tm1Lees/E2f6⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal vertebrae morphology ( J:134271 )

• small extra bone present above C1 in 62% of compound mutant mice

thoracic vertebral transformation ( J:134271 )

• transformation of T7 to T8 and T13 to L1 are seen in 77% and 85% of compound mutant mice, respectively

cervical vertebral transformation ( J:134271 )

• transformation of C1 to C2, C5 to C6, and C7 to T1 are seen in 85%, 23%, and 31% of compound mutant mice, respectively

• partial transformation of C7 to T1 is seen in 77% of compound mutant mice

lumbar vertebral transformation ( J:134271 )

• transformation of L6 to S1 is seen in 92% of compound mutant mice