Phenotypes for Bmi1 E2f6 MGI:3790812 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Bmi1^tm1Brn/Bmi1⁺ E2f6^tm1Lees/E2f6⁺
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmi1^tm1Brn mutation (2 available); any Bmi1 mutation (31 available)
E2f6^tm1Lees mutation (0 available); any E2f6 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

thoracic vertebral transformation ( J:134271 )

• transformation of T7 to T8 and T13 to L1 are seen in 4% and 50% of double heterozygous mice, respectively

cervical vertebral transformation ( J:134271 )

• partial or complete transformation of C7 to T1 is seen in 42% and 8% of double heterozygous mice, respectively

• transformation of C5 to C6 is seen in 4% of double heterozygous mice

lumbar vertebral transformation ( J:134271 )

• transformation of L6 to S1 is seen in 73% of double heterozygous mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24