Phenotypes for Bmi1 E2f6 MGI:3790811 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Bmi1^tm1Brn/Bmi1⁺ E2f6^tm1Lees/E2f6^tm1Lees
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmi1^tm1Brn mutation (2 available); any Bmi1 mutation (31 available)
E2f6^tm1Lees mutation (0 available); any E2f6 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

thoracic vertebral transformation ( J:134271 )

• transformation of T13 to L1 is seen in 77% of compound mutant mice

cervical vertebral transformation ( J:134271 )

• partial or complete transformation of C7 to T1 is seen in 27% and 4% of compound mutant mice, respectively

lumbar vertebral transformation ( J:134271 )

• transformation of L6 to S1 is seen in 92% of compound mutant mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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