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Phenotypes Associated with This Genotype
Genotype
MGI:3789703
Allelic
Composition
Lpltm1Bres/Lpl+
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lpltm1Bres mutation (0 available); any Lpl mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased body weight at all time points measured between 11 and 23 weeks of age
• increase in the fat mass to lean mass ratio
• difference in fat mass to lean mass ratio compared to controls increases over time

adipose tissue
• males have significantly increased fat pad weights compared to controls

homeostasis/metabolism
• females exhibit increased unesterified and total cholesterol levels
• males and females have significantly increased endpoint triglycerides


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory