About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3789198
Allelic
Composition
Apoetm1Unc/Apoetm1Unc
Rag2tm1Fwa/Rag2tm1Fwa
Genetic
Background
involves: 129P2/OlaHsd * 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
Rag2tm1Fwa mutation (46 available); any Rag2 mutation (121 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• body weight of mice treated with estradiol is reduced relative to that of untreated controls

reproductive system
• in response to estradiol treatment

homeostasis/metabolism
• reduced total cholesterol in response to estradiol treatment
• in response to estradiol treatment

cardiovascular system
• increased fatty streak lesions in the aortic root in response to estradiol treatment


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory