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Phenotypes Associated with This Genotype
Genotype
MGI:3789192
Allelic
Composition		 Cd8atm1Mak/Cd8atm1Mak
Genetic
Background		 B6.129S2-Cd8atm1Mak
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8atm1Mak mutation (7 available); any Cd8a mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal response to transplant ( J:91742 )
• skin grafts from OVA expressing transgenic mice ( Tg(CAG-OVA)916Jen) shrink rapidly to 10-30% of their original size on mutant hosts but are then retained indefinitely in healthy condition

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory