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Phenotypes Associated with This Genotype
Genotype
MGI:3784571
Allelic
Composition		 Car2n/Car2n
Car9tm1Spas/Car9tm1Spas
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Car2n mutation (1 available); any Car2 mutation (21 available)
Car9tm1Spas mutation (1 available); any Car9 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, incomplete penetrance ( J:102478 )
• only one of 10 expected mice is born

digestive/alimentary system
abnormal small intestine crypts of Lieberkuhn morphology ( J:102478 )
• enlarged crypts of the small intestine
stomach epithelial hyperplasia ( J:102478 )
• mild pit-cell hyperplasia of the stomach

endocrine/exocrine glands
abnormal small intestine crypts of Lieberkuhn morphology ( J:102478 )
• enlarged crypts of the small intestine

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory