Analysis Tools
behavior/neurological
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• mice consume food slower in a new environment than Tg(GFAP-APOE_i4)#Hol Apoetm1Unc/Apoetm1Unc and wild-type mice
• mice require more time to habituate to a novel environment compared to wild-type mice
• mice are less reluctant than wild-type mice to move into an open area
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• at 14 to 17 months of age, mice perform better than Tg(GFAP-APOE_i4)#Hol Apoetm1Unc/Apoetm1Unc and wild-type mice in a rotating holeboard test
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• mice exhibit increased protected risk assessment behaviors in an elevated plus maze compared to wild-type mice
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• compared to wild-type mice
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• mice exhibit increased numbers of fine movement (not related to ambulation) compared to wild-type mice
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• mice spend less time than wild-type mice in the center of an open field
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