Phenotypes Associated with This Genotype

Genotype
MGI:3783805

• Allelic Composition: Tg(APOA1)1Rub/0; Tg(APOA2)3Rub/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased cholesterol efflux ( J:129136 )

• compared to in Apoa1^tm1Unc homozygotes with or without Tg(APOA2)3Rub

homeostasis/metabolism

increased cholesterol efflux ( J:129136 )

• compared to in Apoa1^tm1Unc homozygotes with or without Tg(APOA2)3Rub

decreased circulating cholesterol level ( J:121992 )

decreased circulating HDL cholesterol level ( J:121992 )

increased circulating cholesterol level ( J:129136 )

• compared to in Apoa1^tm1Unc homozygotes with or without Tg(APOA2)3Rub

increased circulating HDL cholesterol level ( J:129136 )

• compared to in Apoa1^tm1Unc homozygotes with or without Tg(APOA2)3Rub

increased circulating triglyceride level ( J:129136 )

• compared to in Apoa1^tm1Unc homozygotes with or without Tg(APOA2)3Rub