Phenotypes Associated with This Genotype

Genotype
MGI:3783777

• Allelic Composition: H2-K^bm1/H2-K^bm1; Tg(TcraTcrb)1100Mjb/?
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal positive T cell selection ( J:92867 )

• the transgenic TCR does not have a high affinity for the H2-K^bm1 allele leading to poor selection of T cell precursors for the CD8 single positive subset

hematopoietic system

abnormal positive T cell selection ( J:92867 )

• the transgenic TCR does not have a high affinity for the H2-K^bm1 allele leading to poor selection of T cell precursors for the CD8 single positive subset