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Phenotypes Associated with This Genotype
Genotype
MGI:3783771
Allelic
Composition		 Apoa1tm1Unc/Apoa1tm1Unc
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoa1tm1Unc mutation (2 available); any Apoa1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:2109 )
• at 8 weeks of age, total cholesterol levels are decreased to 33% of wild-type
decreased circulating HDL cholesterol level ( J:2109 )
• at 8 weeks of age, HDL levels are decreased to 17% of wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory