Phenotypes for Ptch1 Shh MGI:3783757 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ptch1^tm1Mps/Ptch1⁺ Shh^tm6Amc/Shh^tm6Amc
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptch1^tm1Mps mutation (2 available); any Ptch1 mutation (115 available)
Shh^tm6Amc mutation (1 available); any Shh mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:132152 )

• significantly normalized the size of each neural progenitor domains and the gross phenotype of Shh^tm6Amc/Shh^tm6Amc homozygous mice

• authors did not mention whether the prenatal lethality phenotype found in Shh^tm6Amc/Shh^tm6Amc homozygous mice was rescued or not

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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