reproductive system
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• rete testis dilated compared to wild-type, with equal or greater volume compared to Esr1-null mice
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• ductules dilated compared to wild-type, with equal or greater volume compared to Esr1-null mice
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• fertility is reduced with aging
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endocrine/exocrine glands
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• rete testis dilated compared to wild-type, with equal or greater volume compared to Esr1-null mice
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