Analysis Tools
immune system
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• the majority of T cells in the thymus are arrested at the double positive stage
• single positive T cells are virtually absent
• however, the TCR transgene rescues the arrestment of T cells in the double negative stage that occurs in Rag2 deficient background
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• mature CD4 T cells are severely reduced in the spleen
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• mature CD8 T cells are virtually absent in the spleen
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hematopoietic system
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• the majority of T cells in the thymus are arrested at the double positive stage
• single positive T cells are virtually absent
• however, the TCR transgene rescues the arrestment of T cells in the double negative stage that occurs in Rag2 deficient background
|
|
• mature CD4 T cells are severely reduced in the spleen
|
|
• mature CD8 T cells are virtually absent in the spleen
|
