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Phenotypes Associated with This Genotype
Genotype
MGI:3777352
Allelic
Composition
Cd19tm1(cre)Cgn/Cd19+
Tnfsf13btm1Msc/Tnfsf13btm1Msc
Traf2tm1Rbr/Traf2tm1Rbr
Genetic
Background
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
Tnfsf13btm1Msc mutation (1 available); any Tnfsf13b mutation (28 available)
Traf2tm1Rbr mutation (0 available); any Traf2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• there is about a 4-fold increase in the number of follicular B cells found in the spleen compared to controls
• there are greatly increased numbers of marginal zone B cells in both spleen and lymph nodes

hematopoietic system
• there is about a 4-fold increase in the number of follicular B cells found in the spleen compared to controls
• there are greatly increased numbers of marginal zone B cells in both spleen and lymph nodes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory