Phenotypes Associated with This Genotype

Genotype
MGI:3777346

• Allelic Composition: Nr2e1^tm1Rev/Nr2e1^tm1Rev; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal dentate gyrus morphology ( J:132664 )

• hypomorphic

vision/eye

vision/eye phenotype ( J:132664 )

N • visual function remains at 2-4 months

behavior/neurological

behavior/neurological phenotype ( J:132664 )

N • contextual fear conditioning is normal

abnormal spatial learning ( J:132664 )

• profoundly impaired in a Morris water maze test

abnormal short-term spatial reference memory ( J:132664 )

• deficient short term memory but normal long term memory in a Morris water maze