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Phenotypes Associated with This Genotype
Genotype
MGI:3777343
Allelic
Composition		 Nr2e1tm1Rev/Nr2e1tm1Rev
Tg(CAG-cre/Esr1*)5Amc/?
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2e1tm1Rev mutation (0 available); any Nr2e1 mutation (32 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron differentiation ( J:132664 )
• three weeks of voluntary running results in an increased number of dividing cells in the brain
• reduced pool of neural stem cells

behavior/neurological
behavior/neurological phenotype ( J:132664 )
N
• contextual fear conditioning is normal
• tone-cued memory is normal

cellular
abnormal neuron differentiation ( J:132664 )
• three weeks of voluntary running results in an increased number of dividing cells in the brain
• reduced pool of neural stem cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory