Phenotypes Associated with This Genotype

Genotype
MGI:3776480

• Allelic Composition: Il2rg^tm1Cgn/Y; Rag2^tm1Fwa/Rag2^tm1Fwa
• Genetic Background: B6.129-Rag2^tm1Fwa Il2rg^tm1Cgn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

absent B cells ( J:132257 )

♂ • mice lack all B cells

absent NK cells ( J:132257 )

♂ • mice lack all NK cells

♂ • NK cells that are transferred into these mice are able to proliferate with a lifespan of about 10 days

absent T cells ( J:132257 )

♂ • mice lack all T cells

hematopoietic system

absent B cells ( J:132257 )

♂ • mice lack all B cells

absent NK cells ( J:132257 )

♂ • mice lack all NK cells

♂ • NK cells that are transferred into these mice are able to proliferate with a lifespan of about 10 days

absent T cells ( J:132257 )

♂ • mice lack all T cells