Phenotypes for Cdkn2a Nf1 MGI:3776068 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cdkn2a^tm2.1Rdp/Cdkn2a^tm2.1Rdp Nf1^tm1Tyj/Nf1⁺
Genetic Background	involves: 129S2/SvPas * 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2a^tm2.1Rdp mutation (2 available); any Cdkn2a mutation (62 available)
Nf1^tm1Tyj mutation (3 available); any Nf1 mutation (157 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

neoplasm ( J:131914 )

N	• unlike other mice with at least one Nf1^tm1Tyj allele, mice do not display malignant peripheral nerve sheath tumors or neurofibromas

increased lymphoma incidence ( J:131914 )

• hematopoietic neoplasms, especially lymphoma, are seen in some mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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