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Phenotypes Associated with This Genotype
Genotype
MGI:3775737
Allelic
Composition		 Eomestm1Rob/Eomes+
Nodaltm1Rob/Nodal+
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (44 available)
Eomestm1Rob mutation (0 available); any Eomes mutation (42 available)
Nodaltm1Rob mutation (2 available); any Nodal mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality ( J:131055 )
• severely affected embryos are not recovered

embryo
rostral body truncation ( J:131055 )
• embryos with anterior axis truncations are recovered at low frequency

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory