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Phenotypes Associated with This Genotype
Genotype
MGI:3775442
Allelic
Composition
Sh2d1atm2Vei/Sh2d1atm2Vei
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (8 available); any Cd19 mutation (17 available)
Sh2d1atm2Vei mutation (0 available); any Sh2d1a mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• unlike other conditional knockouts of Apcs, mice exhibit normal numbers of NK T cells, normal antibody response and normal germinal center B cell numbers


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory