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Phenotypes Associated with This Genotype
Genotype
MGI:3775442
Allelic
Composition		 Sh2d1atm2Vei/Sh2d1atm2Vei
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Sh2d1atm2Vei mutation (0 available); any Sh2d1a mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:131618 )
N
• unlike other conditional knockouts of Apcs, mice exhibit normal numbers of NK T cells, normal antibody response and normal germinal center B cell numbers

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory