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Phenotypes Associated with This Genotype
Genotype
MGI:3773292
Allelic
Composition
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa1tm3.1Mrc mutation (0 available); any Hoxa1 mutation (14 available)
Hoxb1tm3Mrc mutation (0 available); any Hoxb1 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• branchiomotor neurons do not fasciculate and exit at multiple points along the neural tube unlike in wild-type mice
• hindbrain organization into even- and odd-numbered rhombomeres is lacking

embryo
• hindbrain organization into even- and odd-numbered rhombomeres is lacking
• some mice exhibit a distortion of the second and third pouch towards the first

craniofacial

endocrine/exocrine glands

hematopoietic system

immune system

cellular
• branchiomotor neurons do not fasciculate and exit at multiple points along the neural tube unlike in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory