Phenotypes Associated with This Genotype

Genotype
MGI:3773051

• Allelic Composition: Cdkn1c^tm1Sje/Cdkn1c⁺; Kcnq1ot1^tm1Tilg/Kcnq1ot1⁺
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:108700 )

N • mice that maternally inherit the mutant Cdkn1c allele do survive to adulthood

cellular

abnormal imprinting ( J:108700 )

• paternal transmission of the deletion mutation leads to the paternal allelic expression of the Cdkn1c gene and prevents the postnatal lethality phenotype associated with Cdkn1c heterozygotes that paternally inherit the wild-type allele