Phenotypes Associated with This Genotype

Genotype
MGI:3772056

• Allelic Composition: Mmp14^tm1Hbh/Mmp14⁺; Mmp16^tm1Khol/Mmp16⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased cranium length ( J:130212 )

• at day 30, the cranium length is reduced to 91% of wild-type

short humerus ( J:130212 )

• at day 20, humerus length is 94+/-1.2% of wild-type

• at day 50, humerus length is 93+/-0.7% of wild-type

abnormal chondrocyte morphology ( J:130212 )

• the number of proliferating chondrocytes in the distal femoral epiphysis decreases proportionally to the number of wild-type alleles lost

limbs/digits/tail

short humerus ( J:130212 )

• at day 20, humerus length is 94+/-1.2% of wild-type

• at day 50, humerus length is 93+/-0.7% of wild-type

craniofacial

decreased cranium length ( J:130212 )

• at day 30, the cranium length is reduced to 91% of wild-type