immune system
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• isolated T cells primed under Th2 conditions for 5 days, restimulated for 5 more days, then restimulated in absence of exogenous cytokine fail to produce Il4, although cell expansion is similar to wild-type; PMA/ionomycin restimulation of Th2-primed cells restores Il4 secretion
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hematopoietic system
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• isolated T cells primed under Th2 conditions for 5 days, restimulated for 5 more days, then restimulated in absence of exogenous cytokine fail to produce Il4, although cell expansion is similar to wild-type; PMA/ionomycin restimulation of Th2-primed cells restores Il4 secretion
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