Phenotypes for Ahsp Hbb-b1 Hbb-b2 MGI:3769340 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Ahsp^tm1Mjwe/Ahsp⁺ Hbb-b1^tm1Unc/Hbb-b1⁺ Hbb-b2^tm1Unc/Hbb-b2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahsp^tm1Mjwe mutation (0 available); any Ahsp mutation (1 available)
Hbb-b1^tm1Unc mutation (2 available); any Hbb-b1 mutation (7 available)
Hbb-b2^tm1Unc mutation (2 available); any Hbb-b2 mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

anemia ( J:94421 )

• embryos are anemic

decreased hematocrit ( J:94421 )

• decreased to 27.5% from ~55% in wild-type embryos

integument

pallor ( J:94421 )

• embryos are pale

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
beta thalassemia		DOID:12241	OMIM:613985	J:94421

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23