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Phenotypes Associated with This Genotype
Genotype
MGI:3769340
Allelic
Composition
Ahsptm1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Genetic
Background
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahsptm1Mjwe mutation (0 available); any Ahsp mutation (1 available)
Hbb-b1tm1Unc mutation (2 available); any Hbb-b1 mutation (4 available)
Hbb-b2tm1Unc mutation (2 available); any Hbb-b2 mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• embryos are anemic
• decreased to 27.5% from ~55% in wild-type embryos

integument
• embryos are pale

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
beta thalassemia DOID:12241 OMIM:187550
OMIM:603902
OMIM:613985
J:94421


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory