growth/size/body
• smaller than litter mate controls
• born in expected Mendelian numbers
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behavior/neurological
nervous system
• at embryonic stages, vesicles were less concentrated at synaptic sites than in controls
• a similar defect was observed in neonates and during the first postnatal week
• the abnormality was transient and barely detectable by the third postnatal week
• neuromuscular junctions formed on schedule
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