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Phenotypes Associated with This Genotype
Genotype
MGI:3766402
Allelic
Composition
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(Mnx1-cre)1Jrs/?
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr2tm1Dor mutation (3 available); any Fgfr2 mutation (88 available)
Tg(Mnx1-cre)1Jrs mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• smaller than litter mate controls
• born in expected Mendelian numbers

behavior/neurological
• exhibited a mild tremor

nervous system
• at embryonic stages, vesicles were less concentrated at synaptic sites than in controls
• a similar defect was observed in neonates and during the first postnatal week
• the abnormality was transient and barely detectable by the third postnatal week
• neuromuscular junctions formed on schedule


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory