Phenotypes for Map3k12 Mycbp2 MGI:3760660 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Map3k12^{Gt(RRN366)Byg}/Map3k12^{Gt(RRN366)Byg} Mycbp2^tm1.1Adia/Mycbp2^tm1.1Adia
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k12^{Gt(RRN366)Byg} mutation (1 available); any Map3k12 mutation (37 available)
Mycbp2^tm1.1Adia mutation (0 available); any Mycbp2 mutation (222 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nervous system morphology ( J:125702 )

• authors state that mice exhibit the same gross morphological defects as observed in Phr1^tm1.1Adia homozygotes

dilated lateral ventricle ( J:125702 )

• lateral ventricles are increased in size

abnormal brain internal capsule morphology ( J:125702 )

• mice lack the axon tract that runs through the internal capsule

absent brain internal capsule ( J:125702 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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