About   Help   FAQ
Phenotypes Associated with This Genotype
B6Brd.Cg-Tyrc-Brd Dp(11Cops3-Rnf112)1Jrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(11Cops3-Rnf112)1Jrl mutation (1 available); any Dp(11Cops3-Rnf112)1Jrl mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
• in an elevated plus maze
• mice exhibit decreased center to total distance ratio explored (0.26+/-0.01 compared to 0.33+/-0.04 in wild-type mice)
• mice exhibit impaired contextual conditioning (12.6+/-2.5% freezing to context compared to 36.0+/-6.5 in wild-type mice)
• mice exhibit decreased vertical activity (305+/-22 incidents compared to 499+/-60 incidences in wild-type mice)
• mice exhibit increased dominance compared with wild-type mice
• however, mice exhibit normal aggression
• 6.5 hours after introducing a paper towel to cages, only half of mice build nest compared with all wild-type mice
• mice exhibit impaired sociability and response to social novelty compared with wild-type mice
• only half of mice vocalize during handling compared with all wild-type mice

nervous system
• at 12 weeks

• at 12 weeks

adipose tissue

Mouse Models of Human Disease
OMIM ID Ref(s)
Potocki-Lupski Syndrome; PTLS 610883 J:138598

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.01
The Jackson Laboratory