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Phenotypes Associated with This Genotype
Genotype
MGI:3723061
Allelic
Composition		 Tg(Rr158-H2-Ead)1Flv/0
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Rr158-H2-Ead)1Flv mutation (0 available)
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity
decreased double-positive T cell number ( J:124574 )
• significantly decreased numbers of CD4+CD8+ thymocytes

immune system
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity
decreased double-positive T cell number ( J:124574 )
• significantly decreased numbers of CD4+CD8+ thymocytes

endocrine/exocrine glands
thymus hypoplasia ( J:124574 )
• mice have drastic reduction in thymic cellularity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory