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Phenotypes Associated with This Genotype
Genotype
MGI:3722644
Allelic
Composition		 Nxf1Mvb1/Nxf1Mvb1
Pitpnavb/Pitpnavb
Genetic
Background		 involves: C57BL/6J * CAST/Ei * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxf1Mvb1 mutation (1 available); any Nxf1 mutation (35 available)
Pitpnavb mutation (1 available); any Pitpna mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:86371 )
N
• lethality observed in Pitpnavb mice is suppressed with mice living past 750 days compared to less than 100 days in Pitnavb homozygotes

nervous system
abnormal neuron morphology ( J:86371 )
• fewer neurons with pathologies were observed than in Pitpnavb/Pitpnavb Nxf1Mvb1-CAST/Ei/Nxf1Mvb1-C57BL/6J mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory