Phenotypes for Cpb2 Plg MGI:3720815 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cpb2^tm1Efp/Cpb2^tm1Efp Plg^tm1Dco/Plg^tm1Dco
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cpb2^tm1Efp mutation (0 available); any Cpb2 mutation (31 available)
Plg^tm1Dco mutation (0 available); any Plg mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal blood coagulation ( J:80114 )

• in an in vitro assay, fibrinolysis activity is increased to 54.9%+/-3.7% compared to 2.3%+/-1.1% in Plg^tm1Dco homozygotes

growth/size/body

decreased body size ( J:80114 )

• mice are runted and have persistent health problems described for Plg^tm1Dco homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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