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Phenotypes Associated with This Genotype
Genotype
MGI:3718030
Allelic
Composition		 Aldh1a1tm1Gdu/Aldh1a1tm1Gdu
Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Aldh1a3tm1Gdu/Aldh1a3tm1Gdu
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aldh1a1tm1Gdu mutation (1 available); any Aldh1a1 mutation (37 available)
Aldh1a2tm1Gdu mutation (1 available); any Aldh1a2 mutation (36 available)
Aldh1a3tm1Gdu mutation (1 available); any Aldh1a3 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal optic cup morphology ( J:108515 )
• at E10.5 the ventral optic vesicle has not invaginated to form a complete optic cup following maternal dietary retinoic acid treatment ending at E8.5
• however, dorsal invagination does occur

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory