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Phenotypes Associated with This Genotype
Genotype
MGI:3717427
Allelic
Composition
Scxtm1.1Stzr/Scxtm1.1Stzr
Tg(Scx-GFP)1Stzr/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scxtm1.1Stzr mutation (0 available); any Scx mutation (12 available)
Tg(Scx-GFP)1Stzr mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• limb tendons are lost with some missing completely and others small and rudimentary
• the extensor digitorium communis tendon ends are the wrist
• the extensor digiti quinti and carpi ulnaris tendons are reduced
• flexor tendons are more severely affected than extensors
• tail tendons are missing
• short tendons in the trunk are reduced or disrupted while long tendons are missing
• intermuscular tendons including the lateral tendious stripes in the rectus abdominis muscle, subscapularis musclea at the ventral side of the scapula, and the middle tendon of the diaphragm can not be detected
• however, anchoring tendons are normal and mice are mobile

behavior/neurological
• mice cannot use their tails

limbs/digits/tail
• tail tendons are missing

skeleton
• limb tendons are lost with some missing completely and others small and rudimentary
• the extensor digitorium communis tendon ends are the wrist
• the extensor digiti quinti and carpi ulnaris tendons are reduced
• flexor tendons are more severely affected than extensors
• tail tendons are missing
• short tendons in the trunk are reduced or disrupted while long tendons are missing
• intermuscular tendons including the lateral tendious stripes in the rectus abdominis muscle, subscapularis musclea at the ventral side of the scapula, and the middle tendon of the diaphragm can not be detected
• however, anchoring tendons are normal and mice are mobile


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory