Phenotypes for Lrp6 MGI:3716638 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lrp6^Cd/Lrp6^Gt(Ex187)Byg
Genetic Background	involves: 129P2/OlaHsd * A

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp6^Cd mutation (0 available); any Lrp6 mutation (94 available)
Lrp6^Gt(Ex187)Byg mutation (1 available); any Lrp6 mutation (94 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Lrp6^Cd/Lrp6^Gt(Ex187)Byg mice reveal a range of phenotypes

mortality/aging

prenatal lethality ( J:101423 )

limbs/digits/tail

kinked tail ( J:101423 )

nervous system

exencephaly ( J:101423 )

skeleton

abnormal vertebrae development ( J:101423 )

• irregular spine with hemivertebrae

vertebral fusion ( J:101423 )

• irregular spine with fused vertebrae

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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