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Phenotypes Associated with This Genotype
Genotype
MGI:3715860
Allelic
Composition
Del(2Hoxd10-Hoxd12)19Ddu/Del(2Hoxd10-Hoxd12)19Ddu
Hoxatm1Ddu/Del(6Hoxa)1Ddu
Tg(Prrx1-cre)1Cjt/0
Genetic
Background
involves: 129S2/SvPas * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd10-Hoxd12)19Ddu mutation (0 available); any Del(2Hoxd10-Hoxd12)19Ddu mutation (0 available)
Del(6Hoxa)1Ddu mutation (0 available); any Del(6Hoxa)1Ddu mutation (0 available)
Hoxatm1Ddu mutation (0 available); any Hoxa mutation (0 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• when Hoxd13 is present, digits form on forelimb in newborn mice
• clear forearm is observed; structure is ill-formed, reduced, and poorly ossified


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory