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Phenotypes Associated with This Genotype
Genotype
MGI:3712644
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Ightm2Mnz/Ightm2Mnz
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
Ightm2Mnz mutation (1 available); any Igh mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell physiology ( J:75653 )
• B cells show no response to NP-Ficoll immunization compared to wild-type CD19 Ightm2Mnz mice or CD19-null Ightm1Mnz mice

hematopoietic system
abnormal B cell physiology ( J:75653 )
• B cells show no response to NP-Ficoll immunization compared to wild-type CD19 Ightm2Mnz mice or CD19-null Ightm1Mnz mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory