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Phenotypes Associated with This Genotype
Genotype
MGI:3712024
Allelic
Composition		 Braftm1Mmcm/Braf+
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Braftm1Mmcm mutation (4 available); any Braf mutation (62 available)
Polr2atm1(cre/ERT2)Bbd mutation (3 available); any Polr2a mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased lung adenoma incidence ( J:121715 )
• with induction of Cre expression from the transgene, multiple adenomatous tumors form in mouse lungs

respiratory system
increased lung adenoma incidence ( J:121715 )
• with induction of Cre expression from the transgene, multiple adenomatous tumors form in mouse lungs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory