Phenotypes for Gt(ROSA)26Sor Myf6 MGI:3710997 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc}/Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc} Myf6^tm1(cre)Mrc/Myf6^tm1(cre)Mrc
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc} mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Myf6^tm1(cre)Mrc mutation (0 available); any Myf6 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:120967 )

• mice die by 6 months of age

neoplasm

neoplasm ( J:120967 )

N	• unlike in other Gt(ROSA)26Sor^tm3(SS18)Mrc homozygously activated mice, no tumors form

muscle

myopathy ( J:120967 )

• myopathy is characterized by abnormal wavy fiber and limited rhabdomyolysis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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