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Phenotypes Associated with This Genotype
Genotype
MGI:3709491
Allelic
Composition		 Mesp2tm1Ysa/Mesp2tm10Ysa
Gt(ROSA)26Sor/?
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor mutation (17 available); any Gt(ROSA)26Sor mutation (1062 available)
Mesp2tm10Ysa mutation (1 available); any Mesp2 mutation (30 available)
Mesp2tm1Ysa mutation (0 available); any Mesp2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
failure of somite differentiation ( J:120635 )
• epithelial somites do not form and the entire somatic mesoderm is caudalized
• however, dermamyotome and sclerotome differentiation is unaffected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory