Phenotypes Associated with This Genotype

Genotype
MGI:3709036

• Allelic Composition: Otof^pga/Otof^pga
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:119820 )

• low auditory startle response

hearing/vestibular/ear

abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )

• hair bundles appeared slightly distorted under light microscopy

• hair bundles are split at times

increased or absent threshold for auditory brainstem response ( J:119820 )

• auditory threshold of more than 90 dB, indicating that lines are severely hearing impaired in 3-weeks old and 2 month old animals

nervous system

abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )

• hair bundles appeared slightly distorted under light microscopy

• hair bundles are split at times