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Phenotypes Associated with This Genotype
Genotype
MGI:3707500
Allelic
Composition		 Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pcp2-cre)756Mro/0
Genetic
Background		 involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm2Brn mutation (3 available); any Rb1 mutation (117 available)
Rbl1tm1Htr mutation (0 available); any Rbl1 mutation (58 available)
Tg(Pcp2-cre)756Mro mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal Purkinje cell morphology ( J:83783 )
• some Purkinje cells show enlarged nuclei with abnormal hourglass or kidney shapes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory