Phenotypes Associated with This Genotype

Genotype
MGI:3707434

• Allelic Composition: Rb1^tm3Tyj/Rb1^tm3Tyj; Tg(Pax6-cre,GFP)2Pgr/0
• Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

increased retina apoptosis ( J:119919 )

• increased apoptosis is seen

abnormal retina morphology ( J:119919 )

• at P12 extensive cell proliferation occurs

• however, by P21 proliferation is no longer detected unlike in mice that also lack Rbl2

cellular

increased retina apoptosis ( J:119919 )

• increased apoptosis is seen