About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3703590
Allelic
Composition		 Fcer1atm1Knt/Fcer1atm1Knt
Tg(SV40/HTLV-FCER1A)1Bhk/0
Genetic
Background		 either: (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcer1atm1Knt mutation (3 available); any Fcer1a mutation (23 available)
Tg(SV40/HTLV-FCER1A)1Bhk mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased vascular permeability ( J:113572 )
• slight change in vascular permeability is observed in anaphylaxis model

immune system
abnormal type I hypersensitivity reaction ( J:113572 )
• mice show a drop in rectal temperature similar to wild-type controls in the model of anaphylaxis; anaphylaxis is restored compared to Fcer1a-null mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory