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Phenotypes Associated with This Genotype
Genotype
MGI:3703447
Allelic
Composition		 Fgfr1tm1Jpa/Fgfr1tm1.1Jpa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm1.1Jpa mutation (0 available); any Fgfr1 mutation (219 available)
Fgfr1tm1Jpa mutation (0 available); any Fgfr1 mutation (219 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
craniofacial phenotype ( J:81179 )
N
• at E9.5, no defects are seen in the early development of the second branchial arch unlike mice homozygous for Fgfr1tm2Jrt
abnormal craniofacial bone morphology ( J:81179 )
• no enhancement in later craniofacial phenotypes relative to mice homozygous for Fgfr1tm1Jrt that carry the Tg(Wnt1-cre)11Rth transgene

digestive/alimentary system

skeleton
abnormal craniofacial bone morphology ( J:81179 )
• no enhancement in later craniofacial phenotypes relative to mice homozygous for Fgfr1tm1Jrt that carry the Tg(Wnt1-cre)11Rth transgene

growth/size/body
cleft palate ( J:81179 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory